Saudi Journal of Gastroenterology
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Year : 2006  |  Volume : 12  |  Issue : 1  |  Page : 34-35

Allgrove syndrome: reports of cases and literature review

1 Department of Surgery, Guilan University of Medicine, Rasht, Iran
2 Department of Medicine, Guilan University of Medicine, Rasht, Iran

Correspondence Address:
Manochehr Aghajanzadeh
Department of General Surgery, Razi Hospital, P O Box 41448-95655, Rasht
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/1319-3767.27743

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We report a series of three mentally-retarded patients who presented with dysphagia, cough and recurrent pulmonary infection, adrenal insufficiency and alacrimia. Investigations included ultrasonography and CT scan of the abdomen, in addition to barium swallow, esophageal manometry and esophagoscopy confirming the diagnosis of achalasia. Glucocorticoid therapy was prescribed whereas alacrimia was managed by lubricants. In two of our patients dysphagia responded to dilatation while the third required cardiomyotomy.

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