Saudi Journal of Gastroenterology
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CASE REPORT
Year : 2014  |  Volume : 20  |  Issue : 6  |  Page : 385-388

IgG4-related sclerosing mesenteritis in a 7-year-old Saudi Girl


1 Department of Pediatric Gastroenterology, King Saud Bin Abdulaziz University for Health Sciences, National Guard Hospital, Jeddah, Saudi Arabia
2 Department of Pathology, King Saud Bin Abdulaziz University for Health Sciences, National Guard Hospital, Jeddah, Saudi Arabia
3 Department of Pediatric Surgery, King Saud Bin Abdulaziz University for Health Sciences, National Guard Hospital, Jeddah, Saudi Arabia
4 Department of Pediatric Immunology, King Saud Bin Abdulaziz University for Health Sciences, National Guard Hospital, Jeddah, Saudi Arabia
5 Department of Pediatric Rheumatology King Saud Bin Abdulaziz University for Health Sciences, National Guard Hospital, Jeddah, Saudi Arabia
6 Department of Pediatric Gastroenterology (Riyad), King Saud Bin Abdulaziz University for Health Sciences, National Guard Hospital, Jeddah, Saudi Arabia

Correspondence Address:
Mohammed Y Hasosah
Department of Pediatric Gastroenterology, Assistant Professor of Pediatric, King Saud Bin Abdulaziz University for Health Sciences/Pediatric Consultant Gastroenterologist, King Abdul Aziz Medical City, National Guard Hospital, Jeddah, PO Box: 8202, Jeddah 21482
Saudi Arabia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1319-3767.145333

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Sclerosing mesenteritis (SM) is a rare, benign inflammatory disorder of unknown etiology, affecting the membranes of the digestive tract that involves lymphoplasmacytic inflammation, fat necrosis, and fibrosis of the mesentery. We report a child patient with a history of recurrent abdominal pain and fever who was found to have an intra-abdominal mass suspicious for malignancy. A tissue biopsy revealed the diagnosis of SM associated with IgG4-related systemic disease. The patient is currently maintained on 5 mg prednisone daily and no recurrence of symptoms was noted during the 24-month follow-up period. We emphasize, therefore, that SM can present clinical challenges and the presence of SM should cue clinicians to search for other coexisting autoimmune disorders that can have various outcomes.


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