Is there any link between atrial arrhythmias and inflammatory bowel disease?
Güray Can1, Nergis Ekmen2, Hatice Can3, Muhammet Fatih Bayraktar4, Muhammed Emin Demirkol5, Meral Akdoğan Kayhan6, Hadi Sasani7
1 Department of Gastroenterology, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey
2 Department of Gastroenterology, Gazi University, Faculty of Medicine, Ankara, Turkey
3 Department of Nephrology, Inönü University, Faculty of Medicine, Malatya, Turkey
4 Department of Cardiology, Bolu Izzet Baysal State Hospital, Bolu, Turkey
5 Department of Internal Medicine, Bolu Abant Izzet Baysal University, Faculty of Medicine, Bolu, Turkey
6 Department of Gastroenterology, Ankara Bilkent City Hospital, University of Health Sciences, Ankara, Turkey
7 Department of Radiology, Tekirdağ Namık Kemal University, Faculty of Medicine, Tekirdağ, Turkey
Dr. Nergis Ekmen
Department of Gastroenterology, Faculty of Medicine, Gazi University, Yenimahalle, Ankara - 60150
Source of Support: None, Conflict of Interest: None
Background: Inflammation plays an important role in the development of cardiovascular disease, including atherosclerosis and arrhythmia. The aim of this study was to evaluate atrial conduction times (ACTs) in patients with inflammatory bowel disease (IBD) in which systemic chronic inflammation is evident.
Methods: In this cross-sectional, prospective, single-center study, 79 IBD patients (51 ulcerative colitis; 28 Crohn's disease) and 70 healthy controls were included. Atrial electromechanical properties were measured by recording simultaneous surface electrocardiography (ECG) with transthoracic echocardiography (ECHO) and tissue Doppler imaging methods. The relationship between age, disease duration, and ACT was evaluated.
Results: There were significantly increased conduction durations of lateral-PA (time interval from the onset of the P-wave on surface ECG to the beginning of the late diastolic wave), septal-PA, tricuspid-PA, and interatrial–electromechanical delay (IA-EMD), right intraatrial EMD, and left intraatrial (LI-EMD) durations in IBD patients (P < 0.001). In IBD patients, there was a positive correlation with age, lateral PA, septal PA, tricuspid PA, IA-EMD, and LI-EMD (P < 0.05). A positive correlation was found between disease duration and only lateral PA and tricuspid PA (P < 0.05).
Conclusion: In IBD patients, prolonged ACT consists a potential risk for severe atrial arrhythmias. ECG and ECHO screening can be useful in identifying risk groups in IBD patients and taking precautions for future cardiac complications.